CLINICAL AND IMMUNOLOGICAL SIGNIFICANCE OF CALPROTECTIN IN ULCERATIVE COLITIS

Authors

  • Маkhamov Маnsujon Маkhmudovich Author
  • Zаkirova Umida Irkinovna Author
  • Аkhmedov Аnаskhоn Аnvarkhon ugli Author

Abstract

Ulcerative colitis (UC) is a chronic inflammatory disease of the colon characterized by inflammation and ulceration of the mucosal layer. The disease follows a relapsing clinical course with periods of remission. Non-invasive, accurate, and cost-effective biomarkers are essential for assessing disease activity and monitoring treatment efficacy.

References

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2. Schoepfer AM, Beglinger C, Straumann A, et al. Fecal calprotectin correlates more closely with the Simple Endoscopic Score for Crohn's disease than CRP, blood leukocytes, and the CDAI. Am J Gastroenterol. 2010;105(1):162-169.

3. Lin JF, Chen JM, Zuo JH, et al. Meta-analysis: Fecal calprotectin for assessment of inflammatory bowel disease activity. Inflamm Bowel Dis. 2014;20(8):1407-1415.

4. D'Haens G, Ferrante M, Vermeire S, et al. Fecal calprotectin is a surrogate marker for endoscopic lesions in inflammatory bowel disease. Inflamm Bowel Dis. 2012;18(12):2218-2224.

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Published

2026-01-15