VITILIGO KASALLIGINING KLINIK KO‘RINISHLARI VA DAVOLASH USULLARI
Keywords:
vitiligo, autoimmun nazariya, melanotsitlar, depigmentatsiya, sitotoksik T-limfotsitlar, autoantitanachalar, klinik ko‘rinishlar, : genetik moyillik, melanotsitlarning autoimmun destruksiyasi, redoks muvozanatining buzilishi.Abstract
Vitiligo — teridagi melanositlarning yo‘qolishi natijasida oq dog‘lar paydo bo‘ladigan surunkali pigmentatsiya buzilishi. Kasallik klinik jihatdan fokal, segmental, generalizatsiyalangan yoki universal shaklda namoyon bo‘ladi, odatda yuz, qo‘l-oyoqlar va tirsaklarda uchraydi. Ko‘pincha og‘riqsiz bo‘lsa-da, qichishish yoki noqulaylik kuzatilishi mumkin. Vitiligo ko‘pincha autoimmun kasalliklar bilan bog‘liq bo‘ladi. Davolash usullari pigmentatsiyani tiklash va kasallik progressiyasini to‘xtatishga qaratilgan bo‘lib, tropikal dorilar, fototerapiya, melanotsit yoki epidermal transplantatsiya hamda kosmetik choralarni o‘z ichiga oladi. Individual yondashuv va erta davolash bemorning klinik natijalari va hayot sifatini yaxshilashda muhimdir.
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