ARTERIAL GIPERTONIYA ETIOLOGIYASI VA PATOGENEZIGA YANGICHA YONDASHUVLAR
Keywords:
Arterial gipertoniya, etiologiya, patogenez, endotelial disfunksiya, genetik omillar, epigenetika, yallig‘lanish, immun tizimi, ichak mikrobiotasi, neyrogumoral regulyatsiya, RAAS, qon bosimi, zamonaviy yondashuvlar, personalizatsiyalangan davolashAbstract
Mazkur maqolada arterial gipertoniya kasalligining etiologiyasi va patogeneziga doir zamonaviy ilmiy qarashlar tahlil qilingan. An’anaviy omillar bilan bir qatorda, kasallik rivojlanishida genetik va epigenetik mexanizmlar, endotelial disfunksiya, yallig‘lanish jarayonlari, immun tizimi faolligi hamda ichak mikrobiotasining roli keng yoritilgan. Shuningdek, neyrogumoral regulyatsiyaning yangi jihatlari va ularning arterial bosim nazoratidagi ahamiyati ko‘rib chiqilgan. Maqolada ushbu yangi yondashuvlarning klinik amaliyotga ta’siri, xususan, individual davolash strategiyalarini ishlab chiqishdagi o‘rni asoslab berilgan. Tadqiqot natijalari arterial gipertoniyani chuqurroq tushunish va samarali davolash usullarini takomillashtirishga xizmat qiladi.
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