COMPARATIVE ANALYSIS OF MORPHOLOGICAL CHANGES IN THE FRONTAL REGION OF THE CEREBRAL HEMISPHERES IN EXPERIMENTAL OUTBRED RATS UNDER CONDITIONS OF CHRONIC CARBON MONOXIDE INTOXICATION

Authors

  • Bakhronov Shukhrat Yakhyoevich Department of Anatomy and Clinical Anatomy (DCA) of the Bukhara State Medical Institute named after Abu Ali ibn Sina Author
  • Sultonova Lola Jakhonkulovna Department of Anatomy and Clinical Anatomy (DCA) of the Bukhara State Medical Institute named after Abu Ali ibn Sina. Author

Keywords:

Materials and methods. The study was conducted on 40 outbred male rats aged 3 and 18 months. The animals were divided into control and experimental groups according to age and study design.

Abstract

Aim of the study. To identify morphological and morphometric alterations developing in the frontal region of the cerebral hemispheres in experimental outbred rats of different ages exposed to chronic carbon monoxide intoxication and to compare the obtained findings with those of the control group.

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References

1. Belyaeva E.A., Sokolov A.A., Makarov I.V. Cellular mechanisms of hypoxic brain injury under carbon monoxide exposure. Bulletin of Experimental Biology and Medicine. 2020;169(4):512–516.

2. Mirzaev A.M., Khasanov Sh.T. Morphofunctional changes in aging neurons during chronic intoxication. Morphology. 2021;159(2):73–79.

3. Zhai J., Li M., Wang X. Oxidative stress-mediated neuronal injury induced by carbon monoxide poisoning. Oxidative Medicine and Cellular Longevity. 2021;2021:Article ID 9945231.

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Published

2026-06-12

Issue

Vol. 5 No. 49 (2026): THEORY AND ANALYTICAL ASPECTS OF RECENT RESEARCH

Section

Articles